About ISB


Publication: 2013-07-02


Our Mantra: No one does science the way ISB does science.


Name:Owen Ambur


Name:Institute for Systems Biology


The Institute for Systems Biology is a premier, nonprofit research organization based in Seattle, Washington.


  • Leroy HoodIt was founded in 2000 by Leroy Hood, a world-renowned systems biologist; Alan Aderem, a leading immunologist; and Ruedi Aebersold, a cutting-edge protein chemist. ABOUT DR. LEE HOOD Dr. Hood is a pioneer in the systems approach to biology and medicine. His research has focused on the study of molecular immunology, biotechnology and genomics. Dr. Hood's professional career began at Caltech, where he and his colleagues developed the DNA gene sequencer and synthesizer and the protein synthesizer and sequencer--four instruments that paved the way for the successful mapping of the human genome. A pillar in the biotechnology field, Dr. Hood has played a role in founding more than fourteen biotechnology companies, including Amgen, Applied Biosystems, Darwin, The Accelerator and Integrated Diagnostics. He is a member of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine. Of the 6,000+ scientists world-wide who belong to one or more of these academies, Dr. Hood is one of only fifteen people accepted to all three. He is also a member of the American Philosophical Society and a Fellow of the American Academy of Arts and Sciences. His work has been widely published, and he has coauthored numerous textbooks in biochemistry, immunology, molecular biology and genetics, as well as a popular book on the human genome project, The Code of Codes. He is the recipient of numerous awards, including the Lasker Award for Studies of Immune Diversity, the Kyoto Prize in advanced technology, the Heinz Award for pioneering work in Systems Biology, and the coveted NAE 2011 Fritz J. and Delores H. Russ Prize for automating DNA sequencing that revolutionized biomedicine and forensic science. In addition to having received 17 honorary degrees from prestigious universities in the US and abroad, Dr. Hood has published more than 700 peer reviewed articles and currently holds 36 patents. He received the 2011 National Medal of Science, which was awarded to him during a White House ceremony in February 2013.

  • Ruedi AebersoldCo-founder

  • Nitin Baliga, PhDSenior Vice President and Director

  • Nathan Price, PhDAssociate Director

  • James R. LaddSenior Vice President for Finance and Operations

  • Sissy Walsh Bouchard, EdDVice President for Development

  • Rob LipshutzSenior Vice President for Strategic Partnerships & Chief Business Officer

  • ISB Board of Directors

  • Louis G. Lange, MD, PhDChairman of the Board - Senior Advisor, Gilead

  • Mark AshidaCEO, Symform

  • Bill BowesCo-Founder, U.S. Venture Partners

  • Thomas J. CableBoard Member, Omeros Corporation

  • Stephen M. GrahamManaging Partner, Seattle Office, Fenwick & West LLP

  • Leroy Hood, MD, PhDPresident, Institute for Systems Biology

  • Douglas HowePresident, Touchstone Corporation

  • Daniel T. LingRetired, Microsoft Research, Corporate Vice President

  • Craig MundieSenior Advisor to the CEO, Microsoft

  • Robert T. NelsenCo-founder and Managing Director, ARCH Venture Partners

  • Roger Perlmutter, MD, PhD
Executive Vice President and President, Merck Research Laboratories

  • J. Leighton Read, MDGeneral Partner, Alloy Ventures

  • David A. SabeyPresident, Sabey Corporation & Sabey Construction

  • Drew Senyei, MDManaging Director, Enterprise Partners Venture Capita

  • ISB Directors Emeriti

  • Steve Clifford

  • Fred Frank

  • Chuck Hirsch

  • Garry Menzel, PhD

  • George Rathmann, PhD

  • Hank Riggs

  • H. Jon Runstad

  • ISB Faculty

  • John AitchisonJohn Aitchison Group -- Complex molecular machines, cell biology, influenza

  • Nitin BaligaNitin Baliga Group -- Systems biology of organism-environment interactions

  • Aimée DudleyAimée Dudley Group -- Genetics, gene regulatory networks, technology development

  • Lee HoodLee Hood Group -- Adaptive immunity, genomics, and biotechnology

  • Sui HuangSui Huang Group -- Molecular and cell biology, cancer biology, gene regulatory networks and theory of complex systems

  • Robert MoritzRobert Moritz Group -- Proteomics, protein chemistry, technology development

  • Adrian OzinskyAdrian Ozinsky Group -- Immunology, cell biology and biotechnology

  • Nathan PriceNathan Price Group -- Computational biology, biochemical reaction networks, genome-scale models, translational bioinformatics

  • Jeff RanishJeff Ranish Group -- Proteomics, macromolecular complexes and transcriptional regulation

  • Ilya ShmulevichIlya Shmulevich Group -- Computational biology, signal and image processing

  • Kai WangPrincipal Scientist

  • ISB Senior Research Scientists & Engineers

  • Gareth CromieGenome Assembly QTL Mapping

  • Kerry Deutsch

  • Eric DeutschDatabase design Proteomics

  • Richard GelinasStem Cell Biology Cell and Molecular Biology

  • Gustavo GlusmanComputational Genomics and Transcriptomics

  • Nat GoodmanComputational biology Software/database development

  • Andrew KellerComputational Biology Proteomics

  • Chris LaustedInstrumentation and Microarray technology

  • Inyoul LeeGenomics, Prion disease biology

  • William LongabaughSoftware engineering, computer graphics, software applications development

  • Monica OrellanaOceanography Phytoplankton physiological ecology

  • Christopher PlaisierHuman Genetics, Gene Expression, Computational Biology, Bioinformatics, Statistics

  • Shizhen QinGenomics, Proteomics

  • David ReissComputational Biology

  • Jared RoachComputational Biology Genetics Genomics Immunology

  • Hector RoviraEnterprise and Web Software Development

  • Lee RowenGenomics

  • Arian SmitGenomics Computational Biology

  • Jennifer SmithGenomics Cell Biology

  • Sergey Stolyar

  • Vesteinn ThorssonComputational Biology

  • Qiang TianCancer and Stem Cell Biology, Translational Systems Medicine

  • Kathie WaltersVirology, genomics, host-pathogen interactions

  • Julian WattsCell Biology and Proteomics

  • Wei YanProteomics, Biochemistry

  • ISB Affiliate Faculty

  • Alan AderemSeattle BioMed, HIV/AIDS, Immunology, Systems Biology

  • Ruedi AebersoldInstitute of Molecular Systems Biology, Proteomics, Protein Chemistry

  • Rudi BallingLuxembourg Centre for Systems Biomedicine, Systems Biology

  • Richard BonneauNew York University's Center for Comparative Functional Genomics, Computational Biology and Structural Biology

  • Jung-Hsien ChiangNational Cheng Kung University Department of Computer Science and Information Engineering, Bioinformatics, Text Mining, Pattern Clustering, and Modeling of Systems Biology Problems

  • Nick FlannUtah State University Department of Computer Science, Modeling Multiscale Systems

  • Timothy GalitskiEMD Millipore, Microbiology, Genetics of Systems Biology

  • Carl HansenUniversity of British Columbia Department of Physics and Astronomy, Physics

  • Stu KauffmanUniversity of Vermont, Tampere University of Technology and Santa Fe Institute, Developmental Biology, Combinatorial Chemistry, Molecular Evolution

  • Gilbert OmennUniversity of Michigan, Clinical Informatics, Databases and Computing, Medical and Translational Research, Proteomics, and Systemic Modeling and Systems Biology

  • Peter SmallBill & Melinda Gates Foundation, Infectious diseases, comparative genomics, bacterial population genetics

  • Ger van den EnghBD BioSciences, Biophysics, Advanced Cytometry, Use of flow cytometry in environmental microbiology

  • Olli Yli-HarjaTampere University of Technology Department of Signal Processing, Computational Systems Biology

  • ISB Scientific Advisory Board

  • Eric H. Davidson, Ph.D.California Institute of Technology

  • Trey Ideker, Ph.D.University of California, San Diego

  • C. Ronald Kahn, M.D., D.Sc.Harvard Medical School

  • Ed Lazowksa, Ph.D.University of Washington

  • Bernhard Ø. Palsson, Ph.D.University of California, San Diego

  • Stephen Quake, Ph.D.Stanford University

  • Ellen Rothenberg, Ph.D.California Institute of Technology

  • Gregory Stephanopoulos, Ph.D.Massachusetts Institute of Technology

  • Irving L. Weissman, M.D.Stanford University Medical Center

  • BiologistsISB was established as an untraditional institution, where scientific collaboration could take place across disciplines, where biologists and technologists could commingle, and where the future of research and medicine could take foot.

  • Technologists

  • Geneticists

  • Computer Scientists

  • Chemists

  • Engineers

  • Mathematicians

  • Immunologists

  • ISB StaffSince 2000, ISB has grown to more than 230 staffers, which includes 10 faculty members and laboratory groups.